Gene
pitx1
- ID
- ZDB-GENE-060421-3623
- Name
- paired-like homeodomain 1
- Symbol
- pitx1 Nomenclature History
- Previous Names
-
- zgc:136976 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II transcription factor binding activity. Predicted to be involved in anatomical structure morphogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in clubfoot. Is expressed in several structures, including adenohypophyseal placode; head; immature eye; non neural ectoderm; and pelvic fin bud. Orthologous to human PITX1 (paired like homeodomain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox protein Pitx/unc30 | Homeodomain | OAR domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P3F1
|
285 | |||||
|
UniProtKB:A9Y0D5
|
285 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available