Gene
pdyn
- ID
- ZDB-GENE-060417-1
- Name
- prodynorphin
- Symbol
- pdyn Nomenclature History
- Previous Names
-
- fj38c03
- wu:fj38c03
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Exhibits opioid receptor binding activity. Predicted to be involved in chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Predicted to localize to several cellular components, including axon terminus; dendrite; and neuronal cell body. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 23 and temporal lobe epilepsy. Is expressed in brain and hypothalamus. Orthologous to human PDYN (prodynorphin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spinocerebellar ataxia type 23 | Alliance | Spinocerebellar ataxia 23 | 610245 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Opioid neuropeptide precursor | Proenkephalin B |
|---|---|---|---|
|
UniProtKB:A0A8M3B6F1
|
253 | ||
|
UniProtKB:Q6JT77
|
252 | ||
|
UniProtKB:A0A8M3AYT0
|
261 |
Interactions and Pathways
No data available
Plasmids
No data available