Gene
slc39a14
- ID
- ZDB-GENE-060315-2
- Name
- solute carrier family 39 member 14
- Symbol
- slc39a14 Nomenclature History
- Previous Names
-
- ZIP14 (1)
- sb:cb823
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable monoatomic anion:monoatomic cation symporter activity and transition metal ion transmembrane transporter activity. Acts upstream of or within manganese ion homeostasis. Located in plasma membrane. Is expressed in neurogenic placode; notochord; presumptive telencephalon; pronephric duct; and somite. Human ortholog(s) of this gene implicated in hypermanganesemia with dystonia 2. Orthologous to human SLC39A14 (solute carrier family 39 member 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb823 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypermanganesemia with dystonia 2 | Alliance | Hypermanganesemia with dystonia 2 | 617013 |
| ?Hyperostosis cranalis interna | 144755 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc/iron permease | Zinc Iron Protein (ZIP) Transporter |
|---|---|---|---|
|
UniProtKB:A0A8M9Q926
|
494 | ||
|
UniProtKB:A0A2R8Q9W7
|
494 | ||
|
UniProtKB:A0A0G2KQY6
|
494 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc39a14-201
(1)
|
Ensembl | 2,143 nt | ||
| mRNA |
slc39a14-202
(1)
|
Ensembl | 1,784 nt | ||
| mRNA |
slc39a14-203
(1)
|
Ensembl | 1,784 nt |
Interactions and Pathways
No data available
Plasmids
No data available