Gene

usp12a

ID

ZDB-GENE-060228-3

Name

ubiquitin specific peptidase 12a

Symbol

usp12a Nomenclature History

Previous Names

usp12
sb:eu882
wu:fi09d12

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to enable cysteine-type deubiquitinase activity and cysteine-type endopeptidase activity. Predicted to be involved in protein deubiquitination and regulation of protein stability. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol and nucleus. Orthologous to human USP12 (ubiquitin specific peptidase 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu882 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With usp12a Human Ortholog

No data available

Associated With usp12a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018200	Ubiquitin specific protease, conserved site
Domain	IPR001394	Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain	IPR028889	Ubiquitin specific protease domain
Family	IPR050164	Ubiquitin carboxyl-terminal hydrolases
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily