Gene
grm6a
- ID
- ZDB-GENE-060208-1
- Name
- glutamate receptor, metabotropic 6a
- Symbol
- grm6a Nomenclature History
- Previous Names
-
- grm6
- mglur6a (1)
- si:dkey-52h10.3
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1B. Is expressed in brain and retinal neural layer. Orthologous to human GRM6 (glutamate metabotropic receptor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital stationary night blindness 1B | Alliance | Night blindness, congenital stationary (complete), 1B, autosomal recessive | 257270 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017979 | GPCR, family 3, conserved site |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR011500 | GPCR, family 3, nine cysteines domain |
| Domain | IPR017978 | GPCR family 3, C-terminal |
| Family | IPR000162 | GPCR, family 3, metabotropic glutamate receptor |
| Family | IPR000337 | GPCR, family 3 |
| Family | IPR001786 | GPCR, family 3, metabotropic glutamate receptor 4 |
| Family | IPR050726 | Metabotropic Glutamate Receptor |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
| Homologous_superfamily | IPR038550 | GPCR, family 3, nine cysteines domain superfamily |
Domain Details Per Protein
| Protein | Length | GPCR, family 3 | GPCR, family 3, conserved site | GPCR family 3, C-terminal | GPCR, family 3, metabotropic glutamate receptor | GPCR, family 3, metabotropic glutamate receptor 4 | GPCR, family 3, nine cysteines domain | GPCR, family 3, nine cysteines domain superfamily | Metabotropic Glutamate Receptor | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B0UYJ3
|
907 | ||||||||||
|
UniProtKB:A0A0R4IRN2
|
908 |
Interactions and Pathways
No data available
Plasmids
No data available