Gene
dock4b
- ID
- ZDB-GENE-060130-74
- Name
- dedicator of cytokinesis 4b
- Symbol
- dock4b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in cell chemotaxis. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human DOCK4 (dedicator of cytokinesis 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu488 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR027007 | C2 DOCK-type domain |
| Domain | IPR027357 | DOCKER domain |
| Domain | IPR032376 | Dedicator of cytokinesis, N-terminal domain |
| Domain | IPR035769 | Dedicator of cytokinesis 4, SH3 domain |
| Domain | IPR037014 | Dedicator of cytokinesis protein 4, DHR2 domain |
| Domain | IPR037811 | Dedicator of cytokinesis B, C2 domain |
| Domain | IPR046770 | DOCKER, Lobe B |
| Domain | IPR046773 | DOCKER, Lobe C |
| Family | IPR026791 | Dedicator of cytokinesis |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR042455 | Dedicator of cytokinesis, N-terminal, subdomain 1 |
| Homologous_superfamily | IPR043161 | Dedicator of cytokinesis, C-terminal, lobe A |
| Homologous_superfamily | IPR043162 | Dedicator of cytokinesis, C-terminal, lobe C |
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | C2 DOCK-type domain | C2 domain superfamily | Dedicator of cytokinesis | Dedicator of cytokinesis 4, SH3 domain | Dedicator of cytokinesis B, C2 domain | Dedicator of cytokinesis, C-terminal, lobe A | Dedicator of cytokinesis, C-terminal, lobe C | Dedicator of cytokinesis, N-terminal domain | Dedicator of cytokinesis, N-terminal, subdomain 1 | Dedicator of cytokinesis protein 4, DHR2 domain | DOCKER domain | DOCKER, Lobe B | DOCKER, Lobe C | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A286Y8M9
|
1953 | ||||||||||||||||
|
UniProtKB:A0A8M2BC66
|
1930 | ||||||||||||||||
|
UniProtKB:E9QJL8
|
1977 | ||||||||||||||||
|
UniProtKB:A0A8M2BC62
|
1970 | ||||||||||||||||
|
UniProtKB:A0A8M2BC87
|
1938 | ||||||||||||||||
|
UniProtKB:A0A0R4IT43
|
1962 | ||||||||||||||||
|
UniProtKB:A0A8M3B1G3
|
1961 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dock4b-201
(1)
|
Ensembl | 6,111 nt | ||
| mRNA |
dock4b-203
(1)
|
Ensembl | 5,451 nt | ||
| mRNA |
dock4b-204
(1)
|
Ensembl | 10,118 nt | ||
| mRNA |
dock4b-205
(1)
|
Ensembl | 10,177 nt | ||
| mRNA |
dock4b-206
(1)
|
Ensembl | 10,150 nt | ||
| mRNA |
dock4b-207
(1)
|
Ensembl | 10,054 nt | ||
| ncRNA |
dock4b-002
(1)
|
Ensembl | 680 nt |
Interactions and Pathways
No data available
Plasmids
No data available