Gene

arnt

ID

ZDB-GENE-060126-7

Name

aryl hydrocarbon receptor nuclear translocator

Symbol

arnt Nomenclature History

Previous Names

ARNT1 (1)
zfARNT1a (1)
zfARNT1b (1)
zfARNT1c (1)
zgc:136664

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including positive regulation of DNA-templated transcription; regulation of signal transduction; and response to toxic substance. Predicted to be located in cytoplasm. Predicted to be part of aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arnt Human Ortholog

No data available

Associated With arnt Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Domain	IPR013767	PAS fold
Family	IPR001067	Nuclear translocator
Family	IPR050933	Circadian Clock Transcription Factors
Homologous_superfamily	IPR035965	PAS domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily
Repeat	IPR001610	PAC motif

Domain Details Per Protein

Protein	Length	Circadian Clock Transcription Factors	Helix-loop-helix DNA-binding domain superfamily	Myc-type, basic helix-loop-helix (bHLH) domain	Nuclear translocator	PAC motif	PAS domain	PAS domain superfamily	PAS fold
UniProtKB:A0A8M2B455 InterPro	713
UniProtKB:A0A8M2B4Q3 InterPro	746
UniProtKB:Q64FF9 InterPro	503
UniProtKB:Q64FF8 InterPro	404
UniProtKB:Q1JPT1 InterPro	440
UniProtKB:A0A8M2B4T8 InterPro	747

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arnt-201 (1) Ensembl	Ensembl	1,828 nt	Select Tool ZFIN BLAST
mRNA	arnt-202 (1) Ensembl	Ensembl	2,540 nt	Select Tool ZFIN BLAST
mRNA	arnt-203 (1) Ensembl	Ensembl	2,060 nt	Select Tool ZFIN BLAST
mRNA	arnt-204 (1) Ensembl	Ensembl	1,935 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations