Gene
smtlb
- ID
- ZDB-GENE-060123-1
- Name
- somatolactin beta
- Symbol
- smtlb Nomenclature History
- Previous Names
-
- slb
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable growth hormone activity and growth hormone receptor binding activity. Acts upstream of or within pigment granule aggregation in cell center and response to peptide hormone. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in head; hypophysis; and pars intermedia. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease of endocrine system (multiple); diabetic retinopathy; isolated growth hormone deficiency (multiple); and progeria. Orthologous to human CSHL1 (chorionic somatomammotropin hormone like 1); GH1 (growth hormone 1); and GH2 (growth hormone 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Four-helical cytokine-like, core | Somatotropin hormone, conserved site | Somatotropin/prolactin |
|---|---|---|---|---|---|
| UniProtKB:Q330P5 | InterPro | 230 | |||
| UniProtKB:A0AB32U2D2 | InterPro | 255 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | smtlb-001_dup (1) | 696 nt | |||
| mRNA |
smtlb-201
(1)
|
Ensembl | 857 nt |
Interactions and Pathways
No data available
Plasmids
No data available