Gene

irge4

ID

ZDB-GENE-051212-2

Name

immunity-related GTPase family, e4

Symbol

irge4 Nomenclature History

Previous Names

zgc:158767

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have GTP binding activity and GTPase activity. Predicted to localize to membrane.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Sieger et al., 2009

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With irge4 Human Ortholog

No data available

Associated With irge4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR030385	IRG-type guanine nucleotide-binding (G) domain
Family	IPR007743	Immunity-related GTPases-like
Family	IPR051515	Immunity-related GTPase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	Immunity-related GTPase	Immunity-related GTPases-like	IRG-type guanine nucleotide-binding (G) domain	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9P7N2 InterPro	772
UniProtKB:A2RV34 InterPro	385

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	irge4-201 (1) Ensembl	Ensembl		1,865 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations