Gene
wnt7aa
- ID
- ZDB-GENE-051129-1
- Name
- wingless-type MMTV integration site family, member 7Aa
- Symbol
- wnt7aa Nomenclature History
- Previous Names
-
- wnt7a
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have frizzled binding activity. Predicted to be involved in Wnt signaling pathway; cell fate commitment; and neuron differentiation. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in Fuhrmann syndrome. Is expressed in brain; head; otic vesicle; pectoral fin; and pectoral fin bud. Orthologous to human WNT7A (Wnt family member 7A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fuhrmann syndrome | Alliance | Fuhrmann syndrome | 228930 |
| Schinzel type phocomelia | Alliance | Ulna and fibula, absence of, with severe limb deficiency | 276820 |
| ?Santos syndrome | 613005 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt-7 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q4JLT0
|
349 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wnt7aa-201
(1)
|
Ensembl | 3,435 nt |
Interactions and Pathways
No data available
Plasmids
No data available