Gene
syn2b
- ID
- ZDB-GENE-051127-49
- Name
- synapsin IIb
- Symbol
- syn2b Nomenclature History
- Previous Names
-
- zgc:123199
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity. Predicted to be involved in neurotransmitter secretion. Predicted to be located in synaptic vesicle. Predicted to be active in synaptic vesicle membrane. Is expressed in DEL; nervous system; spinal cord neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SYN2 (synapsin II).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from See et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| schizophrenia | Alliance | {Schizophrenia, susceptibility to} | 181500 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019735 | Synapsin, conserved site |
| Domain | IPR020897 | Synapsin, pre-ATP-grasp domain |
| Domain | IPR020898 | Synapsin, ATP-binding domain |
| Family | IPR001359 | Synapsin |
| Homologous_superfamily | IPR013815 | ATP-grasp fold, subdomain 1 |
| Homologous_superfamily | IPR016185 | Pre-ATP-grasp domain superfamily |
| PTM | IPR019736 | Synapsin, phosphorylation site |
Domain Details Per Protein
| Protein | Length | ATP-grasp fold, subdomain 1 | Pre-ATP-grasp domain superfamily | Synapsin | Synapsin, ATP-binding domain | Synapsin, conserved site | Synapsin, phosphorylation site | Synapsin, pre-ATP-grasp domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IJU5
|
695 |
Interactions and Pathways
No data available
Plasmids
No data available