Gene

rhot2

ID

ZDB-GENE-051120-96

Name

ras homolog family member T2

Symbol

rhot2 Nomenclature History

Previous Names

miro2 (1)
zgc:123249

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have GTP binding activity and GTPase activity. Predicted to be involved in several processes, including Rho protein signal transduction; mitochondrial outer membrane permeabilization; and mitochondrion transport along microtubule. Localizes to mitochondrion. Is expressed in female organism; fin bud; and midbrain. Orthologous to human RHOT2 (ras homolog family member T2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rhot2 Human Ortholog

No data available

Associated With rhot2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Domain	IPR005225	Small GTP-binding domain
Domain	IPR013566	Mitochondrial Rho GTPase 1/3, EF hand associated, type-1
Domain	IPR013567	EF hand associated, type-2
Domain	IPR020860	MIRO domain
Family	IPR001806	Small GTPase
Family	IPR003578	Small GTPase Rho
Family	IPR021181	Mitochondrial Rho GTPase
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase