Gene
primpol
- ID
- ZDB-GENE-051113-100
- Name
- primase and polymerase (DNA-directed)
- Symbol
- primpol Nomenclature History
- Previous Names
-
- zgc:123274
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity; nucleotidyltransferase activity; and transition metal ion binding activity. Predicted to be involved in DNA metabolic process; R-loop processing; and response to UV. Predicted to act upstream of or within DNA repair. Predicted to be located in replication fork. Predicted to be active in mitochondrial matrix and nucleus. Human ortholog(s) of this gene implicated in myopia. Orthologous to human PRIMPOL (primase and DNA directed polymerase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR044917 | DNA-directed primase/polymerase protein |
Domain Details Per Protein
| Protein | Length | DNA-directed primase/polymerase protein |
|---|---|---|
|
UniProtKB:Q32PL8
|
523 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
primpol-202
(1)
|
Ensembl | 614 nt | ||
| mRNA |
primpol-201
(1)
|
Ensembl | 1,960 nt | ||
| mRNA |
primpol-203
(1)
|
Ensembl | 851 nt |
Interactions and Pathways
No data available
Plasmids
No data available