Gene
gamt
- ID
- ZDB-GENE-051030-97
- Name
- guanidinoacetate N-methyltransferase
- Symbol
- gamt Nomenclature History
- Previous Names
-
- zgc:123136
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have guanidinoacetate N-methyltransferase activity. Predicted to be involved in creatine biosynthetic process. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and yolk. Orthologous to human GAMT (guanidinoacetate N-methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| guanidinoacetate methyltransferase deficiency | Alliance | Cerebral creatine deficiency syndrome 2 | 612736 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Arginine N-methyltransferase 2-like domain | Guanidinoacetate N-methyltransferase | RMT2/GAMT Methyltransferase | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q71N41
|
234 | ||||
|
UniProtKB:A8E5I0
|
234 |
Interactions and Pathways
No data available
Plasmids
No data available