Gene
ngfra
- ID
- ZDB-GENE-050928-1
- Name
- nerve growth factor receptor a (TNFR superfamily, member 16)
- Symbol
- ngfra Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable coreceptor activity; death receptor activity; and nerve growth factor binding activity. Predicted to be involved in Rho protein signal transduction. Predicted to act upstream of or within apoptotic process. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001368 | TNFR/NGFR cysteine-rich region |
| Domain | IPR034046 | Tumor necrosis factor receptor 16, N-terminal |
| Domain | IPR041448 | Tumor necrosis factor receptor member 16, transmembrane domain |
| Family | IPR022325 | Tumour necrosis factor receptor 16 |
| Family | IPR052302 | Neurotrophin receptor-related death domain-containing protein |
Domain Details Per Protein
| Protein | Length | Neurotrophin receptor-related death domain-containing protein | TNFR/NGFR cysteine-rich region | Tumor necrosis factor receptor 16, N-terminal | Tumor necrosis factor receptor member 16, transmembrane domain | Tumour necrosis factor receptor 16 |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q108
|
289 | |||||
|
UniProtKB:E7FGW0
|
346 |
Interactions and Pathways
No data available
Plasmids
No data available