Gene
nde1
- ID
- ZDB-GENE-050913-61
- Name
- nudE neurodevelopment protein 1
- Symbol
- nde1 Nomenclature History
- Previous Names
-
- fb82g01
- im:7141877
- wu:fb82g01
- zgc:114109
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have microtubule binding activity. Involved in regulation of cell projection size. Predicted to localize to centrosome; kinesin complex; and kinetochore. Human ortholog(s) of this gene implicated in lissencephaly. Orthologous to human NDE1 (nudE neurodevelopment protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lissencephaly 4 | Alliance | Lissencephaly 4 (with microcephaly) | 614019 |
| Microhydranencephaly | 605013 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NUDE domain | NUDE family |
|---|---|---|---|
|
UniProtKB:Q4V8W6
|
336 |
Interactions and Pathways
No data available
Plasmids
No data available