Gene
mrpl44
- ID
- ZDB-GENE-050913-59
- Name
- mitochondrial ribosomal protein L44
- Symbol
- mrpl44 Nomenclature History
- Previous Names
-
- zgc:114114
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable double-stranded RNA binding activity and ribonuclease III activity. Predicted to be involved in mitochondrial translational elongation. Predicted to act upstream of or within rRNA processing. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 16. Orthologous to human MRPL44 (mitochondrial ribosomal protein L44).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Burkhalter et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 16 | Alliance | Combined oxidative phosphorylation deficiency 16 | 615395 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein mL44, dsRNA binding domain, metazoa | Large ribosomal subunit protein mL44, endonuclease domain | Ribonuclease III, endonuclease domain superfamily |
|---|---|---|---|---|
|
UniProtKB:F1RB48
|
332 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mrpl44-201
(1)
|
Ensembl | 1,185 nt | ||
| mRNA |
mrpl44-202
(1)
|
Ensembl | 1,378 nt |
Interactions and Pathways
No data available
Plasmids
No data available