Gene

herpud1

ID

ZDB-GENE-050913-47

Name

homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Symbol

herpud1 Nomenclature History

Previous Names

zgc:114134

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable transmembrane transporter binding activity. Predicted to be involved in several processes, including endoplasmic reticulum calcium ion homeostasis; endoplasmic reticulum unfolded protein response; and regulation of response to endoplasmic reticulum stress. Predicted to act upstream of or within response to unfolded protein. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in telencephalon. Orthologous to human HERPUD1 (homocysteine inducible ER protein with ubiquitin like domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Diotel et al., 2015

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With herpud1 Human Ortholog

No data available

Associated With herpud1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000626	Ubiquitin-like domain
Family	IPR039751	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 /2
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily

Domain Details Per Protein

Protein	Length	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 /2	Ubiquitin-like domain	Ubiquitin-like domain superfamily
UniProtKB:A0A286YAA4 InterPro	408
UniProtKB:A0A8M2B5Q0 InterPro	401
UniProtKB:Q4V8U9 InterPro	402

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	herpud1-201 (1) Ensembl	Ensembl	2,043 nt	Select Tool ZFIN BLAST
aberrant processed transcript	herpud1-202 (1) Ensembl	Ensembl	618 nt	Select Tool ZFIN BLAST
mRNA	herpud1-203 (1) Ensembl	Ensembl	1,243 nt	Select Tool ZFIN BLAST
mRNA	herpud1-204 (1) Ensembl	Ensembl	2,209 nt	Select Tool ZFIN BLAST
mRNA	herpud1-205 (1) Ensembl	Ensembl	5,657 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations