Gene
pacsin1b
- ID
- ZDB-GENE-050913-35
- Name
- protein kinase C and casein kinase substrate in neurons 1b
- Symbol
- pacsin1b Nomenclature History
- Previous Names
-
- pacsin1
- fe25d06
- syndapin I (1)
- wu:fe25d06
- zgc:114042
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable phospholipid binding activity. Acts upstream of or within auditory receptor cell stereocilium organization and cilium assembly. Predicted to be located in several cellular components, including cytoplasmic vesicle membrane; cytosol; and ruffle membrane. Predicted to be active in endosome and plasma membrane. Is expressed in nervous system; post-vent region; presumptive neural retina; and trunk. Orthologous to human PACSIN1 (protein kinase C and casein kinase substrate in neurons 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001060 | FCH domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR031160 | F-BAR domain |
| Domain | IPR035743 | PACSIN1/PACSIN2, SH3 domain |
| Domain | IPR037454 | PACSIN1, F-BAR |
| Homologous_superfamily | IPR027267 | AH/BAR domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | F-BAR domain | FCH domain | PACSIN1, F-BAR | PACSIN1/PACSIN2, SH3 domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B2GTA5
|
445 | |||||||
|
UniProtKB:Q4V920
|
445 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pacsin1b-201
(1)
|
Ensembl | 2,622 nt | ||
| mRNA |
pacsin1b-202
(1)
|
Ensembl | 2,663 nt | ||
| mRNA |
pacsin1b-203
(1)
|
Ensembl | 561 nt | ||
| mRNA |
pacsin1b-204
(1)
|
Ensembl | 1,352 nt |
Interactions and Pathways
No data available
Plasmids
No data available