Gene

mcm6l

ID

ZDB-GENE-050913-141

Name

MCM6 minichromosome maintenance deficient 6, like

Symbol

mcm6l Nomenclature History

Previous Names

MCM6m (1)
zgc:112244

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded 3'-5' DNA helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication; double-strand break repair via break-induced replication; and mitotic DNA replication. Predicted to act upstream of or within DNA duplex unwinding and DNA replication initiation. Predicted to be part of MCM complex. Predicted to be active in nucleus.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112244 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mcm6l Human Ortholog

No data available

Associated With mcm6l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018525	Mini-chromosome maintenance, conserved site
Domain	IPR001208	MCM domain
Domain	IPR027925	MCM, N-terminal domain
Domain	IPR033762	MCM OB domain
Domain	IPR041024	Mcm6, C-terminal winged-helix domain
Domain	IPR041562	MCM, AAA-lid domain
Family	IPR008049	DNA replication licensing factor Mcm6
Family	IPR031327	Mini-chromosome maintenance protein
Homologous_superfamily	IPR012340	Nucleic acid-binding, OB-fold
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase