Gene
macroh2a2
- ID
- ZDB-GENE-050913-114
- Name
- macroH2A.2 histone
- Symbol
- macroh2a2 Nomenclature History
- Previous Names
-
- H2A2 (1)
- h2afy2
- im:6898017
- wu:fa14g05
- zgc:114051
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Exhibits transcription regulatory region DNA binding activity. Involved in brain development. Predicted to localize to nuclear chromatin. Is expressed in brain; central nervous system; retina; and retinal ganglion cell layer. Orthologous to human MACROH2A2 (macroH2A.2 histone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6898017 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Buschbeck et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002589 | Macro domain |
| Domain | IPR007125 | Histone H2A/H2B/H3 |
| Domain | IPR032454 | Histone H2A, C-terminal domain |
| Domain | IPR035796 | Core histone macro-H2A, macro domain |
| Family | IPR002119 | Histone H2A |
| Family | IPR021171 | Core histone macro-H2A |
| Homologous_superfamily | IPR009072 | Histone-fold |
| Homologous_superfamily | IPR043472 | Macro domain-like |
Domain Details Per Protein
| Protein | Length | Core histone macro-H2A | Core histone macro-H2A, macro domain | Histone-fold | Histone H2A | Histone H2A, C-terminal domain | Histone H2A/H2B/H3 | Macro domain | Macro domain-like |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q4V914
|
367 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
h2afy2-201
(1)
|
Ensembl | 2,001 nt | ||
| mRNA |
h2afy2-202
(1)
|
Ensembl | 678 nt | ||
| mRNA |
h2afy2-203
(1)
|
Ensembl | 897 nt | ||
| mRNA |
h2afy2-204
(1)
|
Ensembl | 883 nt |
Interactions and Pathways
No data available
Plasmids
No data available