Gene

slc8a3

ID

ZDB-GENE-050810-1

Name

solute carrier family 8 member 3

Symbol

slc8a3 Nomenclature History

Previous Names

ncx3 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in calcium ion import across plasma membrane and sodium ion transmembrane transport. Predicted to act upstream of or within calcium ion transport. Predicted to be located in membrane. Predicted to be active in axon; postsynapse; and sarcolemma. Is expressed in brain; eye; ovary; and somite. Orthologous to human SLC8A3 (solute carrier family 8 member A3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc8a3 Human Ortholog

No data available

Associated With slc8a3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003644	Na-Ca exchanger/integrin-beta4
Domain	IPR004837	Sodium/calcium exchanger membrane region
Domain	IPR032452	Sodium/calcium exchanger domain, C-terminal extension
Family	IPR004836	Sodium/calcium exchanger protein
Family	IPR051171	Calcium/Cation Antiporter
Homologous_superfamily	IPR038081	CalX-like domain superfamily
Homologous_superfamily	IPR044880	NCX, central ion-binding domain superfamily

Domain Details Per Protein

Protein	Length	Calcium/Cation Antiporter	CalX-like domain superfamily	Na-Ca exchanger/integrin-beta4	NCX, central ion-binding domain superfamily	Sodium/calcium exchanger domain, C-terminal extension	Sodium/calcium exchanger membrane region	Sodium/calcium exchanger protein
UniProtKB:B2CZC5 InterPro	917
UniProtKB:B8JHS8 InterPro	917
UniProtKB:A0A8M3BET0 InterPro	922
UniProtKB:A0A8M2B3D4 InterPro	916
UniProtKB:A0A8M2B340 InterPro	923