Gene
dpysl3
- ID
- ZDB-GENE-050720-2
- Name
- dihydropyrimidinase like 3
- Symbol
- dpysl3 Nomenclature History
- Previous Names
-
- CRMP-4 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Acts upstream of or within axon guidance and peripheral nervous system neuron axonogenesis. Predicted to be located in cytoplasm and growth cone. Predicted to be active in cytosol. Is expressed in nervous system; neural plate; spinal cord neural tube; and trigeminal placode. Orthologous to human DPYSL3 (dihydropyrimidinase like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006680 | Amidohydrolase-related |
| Family | IPR011778 | Hydantoinase/dihydropyrimidinase |
| Family | IPR050378 | Metallo-dependent Hydrolases Superfamily |
| Homologous_superfamily | IPR011059 | Metal-dependent hydrolase, composite domain superfamily |
| Homologous_superfamily | IPR032466 | Metal-dependent hydrolase |
Domain Details Per Protein
| Protein | Length | Amidohydrolase-related | Hydantoinase/dihydropyrimidinase | Metal-dependent hydrolase | Metal-dependent hydrolase, composite domain superfamily | Metallo-dependent Hydrolases Superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q52PJ5
|
567 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dpysl3-201
(1)
|
Ensembl | 5,023 nt | ||
| mRNA |
dpysl3-202
(1)
|
Ensembl | 689 nt |
Interactions and Pathways
No data available
Plasmids
No data available