Gene
cyp26c1
- ID
- ZDB-GENE-050714-2
- Name
- cytochrome P450, family 26, subfamily C, polypeptide 1
- Symbol
- cyp26c1 Nomenclature History
- Previous Names
-
- cyp26b1l
- cyp26d1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have C-22 sterol desaturase activity and monooxygenase activity. Involved in several processes, including circulatory system development; retinoic acid metabolic process; and rhombomere 4 morphogenesis. Human ortholog(s) of this gene implicated in focal dermal hypoplasia. Is expressed in several structures, including brain; eye; hindbrain neural keel; optic cup; and pleuroperitoneal region. Orthologous to human CYP26C1 (cytochrome P450 family 26 subfamily C member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 38 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Montalbano et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Focal facial dermal dysplasia 4 | 614974 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group IV | Cytochrome P450 superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A1L1M2
|
554 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| antisense |
ottdart00000055385
(1)
|
Ensembl | 497 nt | ||
| mRNA |
cyp26c1-201
(1)
|
Ensembl | 4,032 nt | ||
| mRNA |
cyp26c1-202
(1)
|
Ensembl | 1,689 nt |
Interactions and Pathways
No data available
Plasmids
No data available