Gene

trpc2b

ID

ZDB-GENE-050712-3

Name

transient receptor potential cation channel subfamily C member 2b

Symbol

trpc2b Nomenclature History

Previous Names

trpc2
trpc2a (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be part of cation channel complex. Predicted to be active in plasma membrane. Is expressed in microvillous olfactory receptor neurons; olfactory epithelium; olfactory receptor cell; and olfactory rosette. Orthologous to human TRPC2 (transient receptor potential cation channel subfamily C member 2 (pseudogene)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 9 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trpc2b Human Ortholog

No data available

Associated With trpc2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005821	Ion transport domain
Domain	IPR013555	Transient receptor ion channel domain
Family	IPR002153	Transient receptor potential channel, canonical
Family	IPR005458	Transient receptor potential channel, canonical 2
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily