Gene
spp1
- ID
- ZDB-GENE-050706-97
- Name
- secreted phosphoprotein 1
- Symbol
- spp1 Nomenclature History
- Previous Names
-
- osteopontin (1)
- zgc:111821
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Involved in bone development. Human ortholog(s) of this gene implicated in several diseases, including biliary atresia; coronary artery disease (multiple); disease of cellular proliferation (multiple); multiple sclerosis; and rheumatoid arthritis. Is expressed in several structures, including cranium; heart; opercular flap; osteoblast; and pectoral fin. Orthologous to human SPP1 (secreted phosphoprotein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 52 figures from 42 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Venkatesh et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR002038 | Osteopontin |
Domain Details Per Protein
| Protein | Length | Osteopontin |
|---|---|---|
|
UniProtKB:Q6IVB9
|
305 |
Interactions and Pathways
No data available
Plasmids