Gene

tut1

ID

ZDB-GENE-050706-68

Name

terminal uridylyl transferase 1, U6 snRNA-specific

Symbol

tut1 Nomenclature History

Previous Names

U6 TUTase (1)
zgc:112254 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable RNA adenylyltransferase activity; RNA uridylyltransferase activity; and mRNA 3'-UTR binding activity. Predicted to be involved in mRNA polyadenylation; pre-mRNA cleavage required for polyadenylation; and snRNA processing. Predicted to act upstream of or within mRNA processing. Predicted to be located in nucleolus. Predicted to be active in mitochondrion and nuclear speck. Is expressed in head; ovary; and testis. Orthologous to human TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Kamminga et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tut1 Human Ortholog

No data available

Associated With tut1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR002058	PAP/25A-associated
Domain	IPR003604	Matrin/U1-C-like, C2H2-type zinc finger
Domain	IPR013087	Zinc finger C2H2-type
Domain	IPR034388	Star-PAP, RNA recognition motif
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily
Homologous_superfamily	IPR043519	Nucleotidyltransferase superfamily