Gene
il12ba
- ID
- ZDB-GENE-050525-3
- Name
- interleukin 12Ba
- Symbol
- il12ba Nomenclature History
- Previous Names
-
- il-12p40.a (1)
- il12b
- zgc:152789
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; primary immunodeficiency disease; and salmonellosis. Is expressed in dendritic cell and intestine. Orthologous to human IL12B (interleukin 12B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 29 | Alliance | Immunodeficiency 29, mycobacteriosis | 614890 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III superfamily | Immunoglobulin-like fold | Interleukin-12 beta | Interleukin-12 beta, central domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6F3Q9
|
324 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
il12ba-201
(1)
|
Ensembl | 1,343 nt | ||
| mRNA |
il12ba-202
(1)
|
Ensembl | 1,107 nt | ||
| mRNA |
il12ba-203
(1)
|
Ensembl | 977 nt |
Interactions and Pathways
No data available
Plasmids
No data available