Gene

pygma

ID

ZDB-GENE-050522-482

Name

phosphorylase, glycogen, muscle A

Symbol

pygma Nomenclature History

Previous Names

im:7150327
zgc:110706

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have glycogen phosphorylase activity and pyridoxal phosphate binding activity. Predicted to be involved in glycogen catabolic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease V. Is expressed in several structures, including adaxial cell; eye; heart; integument; and musculature system. Orthologous to human PYGM (glycogen phosphorylase, muscle associated).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7150327 (10 images)
IMAGE:7156459 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Migocka-Patrzałek et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pygma Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
glycogen storage disease V	Alliance	McArdle disease	232600

Associated With pygma Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR035090	Phosphorylase pyridoxal-phosphate attachment site
Family	IPR000811	Glycosyl transferase, family 35
Family	IPR011833	Glycogen/starch/alpha-glucan phosphorylase