Gene
rgrb
- ID
- ZDB-GENE-050522-447
- Name
- retinal G protein coupled receptor b
- Symbol
- rgrb Nomenclature History
- Previous Names
-
- rgr2 (1)
- wu:fb64c10
- zgc:109930
- zgc:92677
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; phototransduction; and visual perception. Predicted to be located in membrane. Is expressed in several structures, including digestive system; endocrine system; optic vesicle; visual system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 44. Orthologous to human RGR (retinal G protein coupled receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92677 (11 images)
- IMAGE:3716658 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 44 | Alliance | Retinitis pigmentosa 44 | 613769 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Retinal pigment epithelium GPCR |
|---|---|---|---|---|---|
|
UniProtKB:Q6DH22
|
291 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available