Gene
tdg.1
- ID
- ZDB-GENE-050522-44
- Name
- thymine DNA glycosylase, tandem duplicate 1
- Symbol
- tdg.1 Nomenclature History
- Previous Names
-
- tdg
- wu:fb44b11
- zgc:110622
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable pyrimidine-specific mismatch base pair DNA N-glycosylase activity and uracil DNA N-glycosylase activity. Predicted to be involved in base-excision repair, AP site formation. Predicted to act upstream of or within DNA repair. Predicted to be active in nucleus. Is expressed in retina. Orthologous to human TDG (thymine DNA glycosylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110622 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Manesia et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | G/T mismatch-specific thymine DNA glycosylasee TDG-like, eukaryotes | Uracil DNA glycosylase family 2 | Uracil-DNA glycosylase-like | Uracil-DNA glycosylase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q503G3
|
441 | ||||
|
UniProtKB:A0A8M2BA24
|
404 |
Interactions and Pathways
No data available
Plasmids
No data available