Gene
homer2
- ID
- ZDB-GENE-050522-417
- Name
- homer scaffold protein 2
- Symbol
- homer2 Nomenclature History
- Previous Names
-
- zgc:111960
- zmp:0000000677 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled glutamate receptor binding activity. Acts upstream of or within olfactory nerve formation and olfactory placode morphogenesis. Predicted to be located in synapse. Predicted to be active in several cellular components, including dendrite; plasma membrane; and postsynaptic density. Is expressed in musculature system; periderm; and somite. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Orthologous to human HOMER2 (homer scaffold protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:111960 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Garaffo et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 68 | Alliance | ?Deafness, autosomal dominant 68 | 616707 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homer, EVH1 domain | Homer family | PH-like domain superfamily | WH1/EVH1 domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A0G2KIM0
|
|||||
|
UniProtKB:F1QT65
|
|||||
|
UniProtKB:F1QU32
|
|||||
|
UniProtKB:Q502P2
|
314 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
homer2-201
(1)
|
Ensembl | 528 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance