Gene
tusc3
- ID
- ZDB-GENE-050522-381
- Name
- tumor suppressor candidate 3
- Symbol
- tusc3 Nomenclature History
- Previous Names
-
- unm_sa1726
- zgc:110044 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Acts upstream of or within magnesium ion transport. Predicted to be located in membrane. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 7. Orthologous to human TUSC3 (tumor suppressor candidate 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110044 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 7 | Alliance | Intellectual developmental disorder, autosomal recessive 7 | 611093 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Oligosaccharyl transferase complex, subunit OST3/OST6 | Thioredoxin-like superfamily |
|---|---|---|---|
|
UniProtKB:A0A8M9QAV6
|
336 | ||
|
UniProtKB:Q503W5
|
300 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance