Gene

exosc6

ID

ZDB-GENE-050522-362

Name

exosome component 6

Symbol

exosc6 Nomenclature History

Previous Names

id:ibd1130
wu:fe17d05
zgc:110071
zgc:77314

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process. Predicted to act upstream of or within rRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Predicted to be active in nucleolus. Is expressed in forebrain; hindbrain; immature eye; midbrain; and optic tectum. Orthologous to human EXOSC6 (exosome component 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110071 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With exosc6 Human Ortholog

No data available

Associated With exosc6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001247	Exoribonuclease, phosphorolytic domain 1
Family	IPR050080	Ribonuclease PH
Homologous_superfamily	IPR020568	Ribosomal protein uS5 domain 2-type superfamily
Homologous_superfamily	IPR027408	PNPase/RNase PH domain superfamily
Homologous_superfamily	IPR036345	Exoribonuclease, PH domain 2 superfamily