Gene

zmynd11

ID

ZDB-GENE-050522-301

Name

zinc finger, MYND-type containing 11

Symbol

zmynd11 Nomenclature History

Previous Names

Bram1 (1)
bs69 (1)
wu:fi38d06 (1)
zgc:110370
zgc:152745

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to enable methylated histone binding activity. Acts upstream of or within SMAD protein signal transduction and negative regulation of BMP signaling pathway. Predicted to be active in nucleus. Is expressed in brain; gut; head; immature eye; and trunk. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 30. Orthologous to human ZMYND11 (zinc finger MYND-type containing 11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Sun et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zmynd11 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant intellectual developmental disorder 30	Alliance	Intellectual developmental disorder, autosomal dominant 30	616083

Associated With zmynd11 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR000313	PWWP domain
Domain	IPR001487	Bromodomain
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR002893	Zinc finger, MYND-type
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR047268	Zinc finger MYND domain-containing protein 11, PWWP domain
Domain	IPR048589	SAM domain-containing protein 1-like, WH domain
Family	IPR047269	Zinc finger MYND domain-containing protein 11
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036427	Bromodomain-like superfamily

Domain Details Per Protein

Protein	Length	Bromodomain	Bromodomain-like superfamily	PWWP domain	SAM domain-containing protein 1-like, WH domain	Zinc finger, FYVE/PHD-type	Zinc finger MYND domain-containing protein 11	Zinc finger MYND domain-containing protein 11, PWWP domain	Zinc finger, MYND-type	Zinc finger, PHD-finger	Zinc finger, PHD-type	Zinc finger, PHD-type, conserved site	Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8M9PG15 InterPro	621
UniProtKB:A0A2R8PVB4 InterPro	629
UniProtKB:Q08CT0 InterPro	640
UniProtKB:Q503P6 InterPro	85
UniProtKB:A0A8M9PXI9 InterPro	464

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	zmynd11-202 (1) Ensembl	Ensembl	3,901 nt	Select Tool ZFIN BLAST
mRNA	zmynd11-205 (1) Ensembl	Ensembl	4,994 nt	Select Tool ZFIN BLAST
ncRNA	zmynd11-002 (1) Ensembl	Ensembl	2,437 nt	Select Tool ZFIN BLAST
ncRNA	zmynd11-003 (1) Ensembl	Ensembl	853 nt	Select Tool ZFIN BLAST
ncRNA	zmynd11-004 (1) Ensembl	Ensembl	1,019 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations