Gene
nup88
- ID
- ZDB-GENE-050522-297
- Name
- nucleoporin 88
- Symbol
- nup88 Nomenclature History
- Previous Names
-
- ik:tdsubc_2f7
- wu:fb16f10
- wu:fb33e09
- xx:tdsubc_2f7
- zgc:112439
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nucleocytoplasmic transport. Predicted to act upstream of or within mRNA transport; nucleocytoplasmic transport; and protein transport. Predicted to be located in nucleus. Predicted to be part of nuclear pore. Is expressed in several structures, including brain; eye; immature eye; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in fetal akinesia deformation sequence syndrome 4. Orthologous to human NUP88 (nucleoporin 88).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| fetal akinesia deformation sequence syndrome 4 | Alliance | Fetal akinesia deformation sequence 4 | 618393 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Nucleoporin Nup88 | Nucleoporin NUP88/NUP82 |
|---|---|---|---|
|
UniProtKB:A0A8D3IZM5
|
|||
|
UniProtKB:A2CEI4
|
720 |
Interactions and Pathways
No data available
Plasmids
No data available