Gene

twf2b

ID
ZDB-GENE-050522-238
Name
twinfilin actin-binding protein 2b
Symbol
twf2b Nomenclature History
Previous Names
  • si:ch211-14i3.4
  • zgc:112092
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and actin monomer binding activity. Predicted to be involved in actin filament depolymerization; negative regulation of actin filament polymerization; and regulation of plasma membrane bounded cell projection organization. Predicted to localize to actin filament and myofibril. Is expressed in lateral line; otic placode; otic vesicle; and posterior lateral line system. Orthologous to human TWF2 (twinfilin actin binding protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With twf2b Human Ortholog
No data available
Associated With twf2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002108 Actin-depolymerising factor homology domain
Family IPR028458 Twinfilin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Domain Details Per Protein
Protein Length Actin-depolymerising factor homology domain ADF-H/Gelsolin-like domain superfamily Twinfilin
UniProtKB:Q502J8 364
UniProtKB:E7F2D6 369
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA twf2b-201 (1) Ensembl 1,540 nt
mRNA twf2b-202 (1) Ensembl 2,581 nt
ncRNA twf2b-002 (1) Ensembl 513 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations