Gene

fcho2

ID
ZDB-GENE-050522-228
Name
FCH and mu domain containing endocytic adaptor 2
Symbol
fcho2 Nomenclature History
Previous Names
  • cb304 (1)
  • sb:cb304
  • si:ch211-195c22.1
  • wu:fa01a02
  • zgc:112167
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have cytoskeletal protein binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and phosphatidylserine binding activity. Involved in chordate embryonic development. Predicted to localize to several cellular components, including clathrin-coated pit; clathrin-coated vesicle; and cytoskeleton. Is expressed in anterior axial hypoblast; hatching gland; immature eye; polster; and yolk syncytial layer. Orthologous to human FCHO2 (FCH and mu domain containing endocytic adaptor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Umasankar et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fcho2 Human Ortholog
No data available
Associated With fcho2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001060 FCH domain
Domain IPR018808 Muniscin, C-terminal
Domain IPR028565 Mu homology domain
Domain IPR030122 F-BAR domain only protein 2, F-BAR domain
Domain IPR031160 F-BAR domain
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036168 AP-2 complex subunit mu, C-terminal superfamily
Domain Details Per Protein
Protein Length AH/BAR domain superfamily AP-2 complex subunit mu, C-terminal superfamily F-BAR domain F-BAR domain only protein 2, F-BAR domain FCH domain Mu homology domain Muniscin, C-terminal
UniProtKB:A0A8M9QDY0 1059
UniProtKB:A0A8M9Q8L9 1044
UniProtKB:A0A8M9Q3B6 862
UniProtKB:A0A8M3ASB7 863
UniProtKB:A0A8M2BJ82 1018
UniProtKB:A0A8M3B2H5 1034
UniProtKB:A0A8M9PXK6 1039
UniProtKB:A0A8M3AZM0 1033
UniProtKB:A0A8M9PK46 1043
UniProtKB:Q502I9 848
UniProtKB:A0A8M3B9M8 843
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fcho2-201 (1) Ensembl 2,547 nt
mRNA fcho2-202 (1) Ensembl 4,099 nt
mRNA fcho2-203 (1) Ensembl 3,291 nt
mRNA fcho2-204 (1) Ensembl 259 nt
mRNA fcho2-205 (1) Ensembl 3,379 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations