Gene

usp48

ID
ZDB-GENE-050522-197
Name
ubiquitin specific peptidase 48
Symbol
usp48 Nomenclature History
Previous Names
  • im:7139343
  • zgc:112364 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity and thiol-dependent ubiquitin-specific protease activity. Involved in cranial skeletal system development. Predicted to localize to cytosol and nucleus. Orthologous to human USP48 (ubiquitin specific peptidase 48).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp48 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 85 Alliance Deafness, autosomal dominant 85 620227
Associated With usp48 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Domain IPR000626 Ubiquitin-like domain
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
Domain IPR028889 Ubiquitin specific protease domain
Domain IPR033841 Ubiquitin-specific peptidase 48
Domain IPR044743 Ubiquitin-specific-processing protease 48, Ubl domain
Family IPR050164 Ubiquitin carboxyl-terminal hydrolases
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR035927 DUSP-like superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length DUSP-like superfamily Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase Peptidase C19, ubiquitin-specific peptidase, DUSP domain Ubiquitin carboxyl-terminal hydrolases Ubiquitin-like domain Ubiquitin-like domain superfamily Ubiquitin-specific peptidase 48 Ubiquitin-specific-processing protease 48, Ubl domain Ubiquitin specific protease, conserved site Ubiquitin specific protease domain
UniProtKB:A0A0R4IB93 1047
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA usp48-201 (1) Ensembl 6,559 nt
mRNA usp48-202 (1) Ensembl 4,226 nt
mRNA usp48-203 (1) Ensembl 1,867 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations