Gene

abcg2d

ID

ZDB-GENE-050517-38

Name

ATP binding cassette subfamily G member 2 (JR blood group)

Symbol

abcg2d Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable ATPase-coupled transmembrane transporter activity; efflux transmembrane transporter activity; and riboflavin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in mitochondrial membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Kobayashi et al., 2008

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcg2d Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Junior blood group system]	614490
		[Uric acid concentration, serum, QTL1]	138900

Associated With abcg2d Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013525	ABC-2 type transporter, transmembrane domain
Domain	IPR043926	ABC transporter family G domain
Family	IPR050352	ATP-binding cassette subfamily G transporters
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase