Gene

abcc5

ID

ZDB-GENE-050517-17

Name

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

Symbol

abcc5 Nomenclature History

Previous Names

fj51h02
mrp5 (1)
si:ch1073-183g13.2
wu:fj51h02

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have ATPase-coupled transmembrane transporter activity. Involved in erythrocyte differentiation and heme transmembrane transport. Predicted to localize to membrane. Is expressed in several structures, including heart; liver; nervous system; pleuroperitoneal region; and solid lens vesicle. Orthologous to human ABCC5 (ATP binding cassette subfamily C member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Korolnek et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcc5 Human Ortholog

No data available

Associated With abcc5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC transporter-like, ATP-binding domain	ABC transporter-like, conserved site	ABC transporter type 1, transmembrane domain	ABC transporter type 1, transmembrane domain superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E7EYG0 InterPro	1426
UniProtKB:E1B2R7 InterPro	1426

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	abcc5-201 (1) Ensembl	Ensembl	4,281 nt	Select Tool ZFIN BLAST
mRNA	abcc5-202 (1) Ensembl	Ensembl	823 nt	Select Tool
ncRNA	abcc5-002 (1) Ensembl	Ensembl	493 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations