Gene

pigl

ID

ZDB-GENE-050506-60

Name

phosphatidylinositol glycan anchor biosynthesis, class L

Symbol

pigl Nomenclature History

Previous Names

im:6902701
si:ch211-202a12.6

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable N-acetylglucosaminylphosphatidylinositol deacetylase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in CHIME syndrome. Orthologous to human PIGL (phosphatidylinositol glycan anchor biosynthesis class L).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6902701 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pigl Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
CHIME syndrome	Alliance	CHIME syndrome	280000

Associated With pigl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR003737	N-acetylglucosaminyl phosphatidylinositol deacetylase-related
Homologous_superfamily	IPR024078	Putative deacetylase LmbE-like domain superfamily