Gene
map3k10
- ID
- ZDB-GENE-050419-112
- Name
- mitogen-activated protein kinase kinase kinase 10
- Symbol
- map3k10 Nomenclature History
- Previous Names
-
- si:ch211-238g23.2
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable JUN kinase kinase kinase activity. Predicted to be involved in positive regulation of apoptotic process. Predicted to act upstream of or within protein phosphorylation. Is expressed in telencephalon. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR035779 | MLK1-3, SH3 domain |
| Family | IPR016231 | Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4 |
| Family | IPR050167 | Serine/threonine-protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4 | MLK1-3, SH3 domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase | Serine/threonine-protein kinase, active site | Serine-threonine/tyrosine-protein kinase, catalytic domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q5J2
|
1062 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map3k10-201
(1)
|
Ensembl | 3,189 nt | ||
| mRNA |
map3k10-202
(1)
|
Ensembl | 2,920 nt |
Interactions and Pathways
No data available
Plasmids
No data available