Gene
pfklb
- ID
- ZDB-GENE-050417-62
- Name
- phosphofructokinase, liver b
- Symbol
- pfklb Nomenclature History
- Previous Names
-
- zgc:110298 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have several functions, including 6-phosphofructokinase activity; adenyl ribonucleotide binding activity; and fructose-6-phosphate binding activity. Predicted to be involved in several processes, including canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and protein homotetramerization. Predicted to localize to 6-phosphofructokinase complex and membrane. Is expressed in liver; male organism; nervous system; somite; and yolk syncytial layer. Orthologous to human PFKL (phosphofructokinase, liver type).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110298 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Hemolytic anemia due to phosphofructokinase deficiency |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR015912 | Phosphofructokinase, conserved site |
Domain | IPR000023 | Phosphofructokinase domain |
Family | IPR009161 | ATP-dependent 6-phosphofructokinase, eukaryotic-type |
Family | IPR022953 | ATP-dependent 6-phosphofructokinase |
Family | IPR041914 | ATP-dependent 6-phosphofructokinase, vertebrate-type |
Homologous_superfamily | IPR035966 | Phosphofructokinase superfamily |
Domain Details Per Protein
Protein | Length | ATP-dependent 6-phosphofructokinase | ATP-dependent 6-phosphofructokinase, eukaryotic-type | ATP-dependent 6-phosphofructokinase, vertebrate-type | Phosphofructokinase, conserved site | Phosphofructokinase domain | Phosphofructokinase superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A0R4ID68
|
779 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available