Gene
apoa4a
- ID
- ZDB-GENE-050417-469
- Name
- apolipoprotein A-IV a
- Symbol
- apoa4a Nomenclature History
- Previous Names
-
- zgc:112992
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylcholine-sterol O-acyltransferase activator activity and phospholipid binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; lipid transport; and very-low-density lipoprotein particle remodeling. Predicted to act upstream of or within lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Predicted to be part of chylomicron and high-density lipoprotein particle. Is expressed in intestine; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Orthologous to human APOA4 (apolipoprotein A4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7160072 (3 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Apolipoprotein A1/A4/E | Apolipoprotein A/E |
|---|---|---|---|
|
UniProtKB:Q566Q0
|
234 | ||
|
UniProtKB:A0A8M9P1T6
|
252 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
apoa4a-201
(1)
|
Ensembl | 1,042 nt | ||
| mRNA |
apoa4a-202
(1)
|
Ensembl | 894 nt | ||
| mRNA |
apoa4a-203
(1)
|
Ensembl | 708 nt |
Interactions and Pathways
No data available
Plasmids