Gene
capn2l
- ID
- ZDB-GENE-050417-341
- Name
- calpain 2, (m/II) large subunit, like
- Symbol
- capn2l Nomenclature History
- Previous Names
-
- wu:fb09d04
- xx:hac23b03
- zgc:112420
- zgc:92480
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within regulation of cytoskeleton organization. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in ectoderm; epidermis; lateral line ganglion; pectoral fin; and pharynx. Orthologous to human CAPN2 (calpain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92480 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR001300 | Peptidase C2, calpain, catalytic domain |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR022682 | Peptidase C2, calpain, large subunit, domain III |
| Domain | IPR022683 | Peptidase C2, calpain, domain III |
| Domain | IPR033883 | Calpain subdomain III |
| Family | IPR022684 | Peptidase C2, calpain family |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR036213 | Calpain large subunit, domain III superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Calpain large subunit, domain III superfamily | Calpain subdomain III | Cysteine peptidase, cysteine active site | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Papain-like cysteine peptidase superfamily | Peptidase C2, calpain, catalytic domain | Peptidase C2, calpain, domain III | Peptidase C2, calpain family | Peptidase C2, calpain, large subunit, domain III |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q561U0
|
700 | |||||||||||
|
UniProtKB:A0A0N4SUE6
|
||||||||||||
|
UniProtKB:Q6DFZ8
|
700 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
capn2l-201
(1)
|
Ensembl | 2,597 nt | ||
| mRNA |
capn2l-202
(1)
|
Ensembl | 2,613 nt |
Interactions and Pathways
No data available
Plasmids
No data available