Gene
b4galt1
- ID
- ZDB-GENE-050417-236
- Name
- UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
- Symbol
- b4galt1 Nomenclature History
- Previous Names
-
- zgc:111810
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Enables galactosyltransferase activity. Acts upstream of or within cell migration involved in gastrulation and notochord morphogenesis. Predicted to be located in Golgi cisterna membrane. Is expressed in lateral mesoderm; olfactory placode; oocyte; and optic vesicle. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId. Orthologous to human B4GALT1 (beta-1,4-galactosyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Machingo et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation type IId | Alliance | Congenital disorder of glycosylation, type IId | 607091 |
| Combined low LDL and fibrinogen | 620364 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Beta-1,4-galactosyltransferase | Galactosyltransferase, N-terminal | Nucleotide-diphospho-sugar transferases |
|---|---|---|---|---|
|
UniProtKB:Q567N4
|
214 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
b4galt1-201
(1)
|
Ensembl | 645 nt | ||
| mRNA |
b4galt1-202
(1)
|
Ensembl | 1,027 nt |
Interactions and Pathways
No data available
Plasmids
No data available