Gene
f3b
- ID
- ZDB-GENE-050417-234
- Name
- coagulation factor IIIb
- Symbol
- f3b Nomenclature History
- Previous Names
-
- TFb (1)
- zgc:112151
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable cytokine receptor activity. Acts upstream of or within vasculature development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in hindbrain and otic vesicle. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; COVID-19; disseminated intravascular coagulation; and von Willebrand's disease. Orthologous to human F3 (coagulation factor III, tissue factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Zhou et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR015373 | Interferon/interleukin receptor domain |
| Family | IPR001187 | Tissue factor |
| Family | IPR050650 | Type II Cytokine and Tissue Factor Receptors |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Interferon/interleukin receptor domain | Tissue factor | Type II Cytokine and Tissue Factor Receptors |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B0UY88
|
288 |
Interactions and Pathways
No data available
Plasmids
No data available