Gene

cart2

ID
ZDB-GENE-050417-23
Name
cocaine- and amphetamine-regulated transcript 2
Symbol
cart2 Nomenclature History
Previous Names
  • cart2a (1)
  • zgc:110124 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have neuropeptide hormone activity. Predicted to be involved in several processes, including activation of MAPKK activity; adult feeding behavior; and negative regulation of appetite. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity. Is expressed in basal plate midbrain region; brain; and neurons. Orthologous to human CARTPT (CART prepropeptide).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cart2 Human Ortholog
No data available
Associated With cart2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR009106 CART satiety factor
Homologous_superfamily IPR036722 CART, C-terminal domain superfamily
Domain Details Per Protein
Protein Length CART, C-terminal domain superfamily CART satiety factor
UniProtKB:Q568S2 120
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cart2-201 (1) Ensembl 684 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations