Gene
agr2
- ID
- ZDB-GENE-050417-214
- Name
- anterior gradient 2
- Symbol
- agr2 Nomenclature History
- Previous Names
-
- sb:eu228
- wu:fj29g05
- zgc:112187
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable identical protein binding activity. Acts upstream of or within intestinal epithelial cell differentiation. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including digestive system; hatching gland; integument; olfactory system; and vestibuloauditory system. Orthologous to human AGR2 (anterior gradient 2, protein disulphide isomerase family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 50 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu228 (13 images)
- IMAGE:7163877 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Chen et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Respiratory infections, recurrent, and failure to thrive with or without diarrhea | 620233 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Anterior Gradient and Thioredoxin Domain | Thioredoxin-like superfamily |
|---|---|---|---|
|
UniProtKB:Q5RZ65
|
171 |
Interactions and Pathways
No data available
Plasmids
No data available